Publicații doctoranzi 2019

Titlul tezei de doctorat: Noi perspective în manegementul patologiilor psihiatrice (depresie majoră, depresie cu elemente psihotice și alzheimer) prin aplicarea combinată a tehnicilor in silico și neuropsihologice

Cod dosar platforma REI: F-CA-15886/22.10.2018

• Putz MV., Duda-Seiman C., Duda-Seiman D., Putz AM., Alexandrescu I., Mernea M., Avram S. 2016. Chemical structure-biological activity Mmodels for pharmacophores’ 3D-interactions. International Journal of Molecular  Science 17 (7), 1087. https://www.mdpi.com/1422-0067/17/7/1087

Alexe Vasile

Titlul tezei de doctorat: Contribuții la cunoașterea biologiei și ecologiei codalbului (Haliaeetus albicilla L.) la gurile de vărsare a Dunării (România)

Cod dosar platforma REI: F-CA-25356/18.10.2019

• Alexe V., Doroşencu C. A., Marinov M., Kiss J. B., Attila D. S., Ceico T., Bolboacă L. E., Tudor M., Nanu C. N., Ivanov G., Enescu R., Moise V., Murariu D. 2019. New Data Regarding the Spatial Distribution of White tailed Eagle (Aves: Haliaeetus albicilla) and their Breeding Ecology between 2009 and 2018 within the Danube Delta Biosphere Reserve and its Surroundings (Romania). Scientific Annals of the Danube Delta Institute, 24, 5-14. http://ddniscientificannals.ddni.ro/scientific-annals/25-volume-24/156-vol21_art03-32

Aramă (Giucă) Mihaela Cristina 

Titlul tezei de doctorat: Investigarea factorilor de virulență ai tulpinilor de Haemophilus influenzae circulante în România

Cod dosar platforma REI: F-CA-15523/11.10.2018

• Giucă MC., Dragomirescu CC., Nica M., Mihăescu G., Gătej IR. 2018. Identification of invasive BLNAR Haemophilus influenzae strain from a patient with acute bronchitis in Romania. Romanian Archives of Microbiology and Immunology 77 (1), 67-72. https://www.researchgate.net/publication/326493273_Identification_of_invasive_BLNAR_Haemophilus_influenzae_strain_from_a_patient_with_acute_bronchitis_in_Romania

Banu Melania Ana

Titlul tezei de doctorat: Dezvoltarea de biochip-uri pentru detecţia şi analiza high-throughput a biomoleculelor

Cod dosar platforma REI: F-CA-16214/30.10.2018

• Banu M., Simion M., Popescu MC., Varasteanu P., Kusko M., Farcasanu IC. 2018. Specific detection of stable single nucleobase mismatch using SU-8 coated silicon nanowires platform. Talanta. 185, 281-290. https://www.sciencedirect.com/science/article/abs/pii/S0039914018303357

Burcea Alexandru

Titlul tezei de doctorat: Analiza moleculară a speciilor de sturioni din Dunăre – aplicații în acvacultură și conservare

Cod dosar platforma REI: F-CA-19272/07.02.2019

• Burcea A., Popa GO., Florescu (Gune) I.E., Gharbia S., Gaina G., Dudu A., Maereanu M., Hermenean A., Georgescu S.E. Costache M. 2018. Gene expression involved in the sexual development of Best Beluga hybrid sturgeons. Journal of Fish Biology 93, 1021-1026. https://onlinelibrary.wiley.com/doi/abs/10.1111/jfb.13815

Burghiu (Pricop) Gabriela Roxana 

Titlul tezei de doctorat:Implicațiile microbiotei anaerobe în infecțiile endogene

Cod dosar platforma REI: F-CA-22293/21.06.2019

• Pricop R., Cristea VC., Gheorghe I., Tatu AL., Mihaescu G., Chifiriuc MC. 2017. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) reveals the anaerobic Slakia exigua as unique etiology of a dental abscess. Biointerface Research in Applied Chemistry 7 (2), 1995-1997. https://biointerfaceresearch.com/?page_id=2015

Chiciudean Iulia

Titlul tezei de doctorat: Studii moleculare pe gene implicate in degradarea microbianl a hidrocarburilor alifatice de origine petrolieriă

Cod dosar platforma REI: F-CA-22221/18.06.2019

• Chiciudean I., Mereuță I., Ionescu R., Vassu T., Tănase A.-M., Stoica I. 2019. Jet A-1 bacterial contamination: A case study of cultivable bacteria diversity, alkane degradation and biofilm formation. Polish Journal of Environmental Sciences. 28 (6), 4139–4146. http://www.pjoes.com/Jet-A-1-Bacterial-Contamination-a-Case-Study-nof-Cultivable-Bacteria-Diversity-Alkane,99108,0,2.html
• Chiciudean I., Nie Y., Tănase AM., Stoica I., Wu XL. 2018. Complete genome sequence of Tsukamurella sp. MH1: A wide-chain length alkane-degrading actinomycete. Journal of Biotechnology, vol. 268, 1-5. https://www.sciencedirect.com/science/article/abs/pii/S0168165617317716?via%3Dihub

Dumitrache (Nae) Ioana 

Titlul tezei de doctorat: Studii morfologice, sistematice şi ecologice, asupra faunei de oribatide (Acari: Oribatida) din mediul subteran superficial, din masivul Piatra Craiului

Cod dosar platforma REI: F-CA-19119/31.01.2019

• Nae I., Băncilă RI. 2017. Mesovoid shallow substratum as a biodiversity hotspot for conservation priorities: analysis of oribatid mite (Acari: Oribatida) fauna. Acarologia 57 (4), 855-868. https://www1.montpellier.inra.fr/CBGP/acarologia/article.php?id=4202

Farhood Hattf Bazool

Titlul tezei de doctorat: The role of chlorogenic acid in the modulation of oxidative stress and inflammation induced by hyperglycemia in liver cells 

Cod dosar platforma REI: F-CA-26562/19.11.2019

• Farhood HB., Balas M., Gradinaru D., Margina D., Dinischiotu A. 2019. Effects of chlorogenic acid on the liver cell metabolism under high glucose conditions. Romanian Biotechnological Letters 24 (5), 883-892. https://www.e-repository.org/rbl/vol.24/iss.5/18.pdf
• Farhood HB., Balas M., Gradinaru D., Margina D., Dinischiotu A., 2019. Hepatoprotective effects of chlorogenic acid under hyperglycemic conditions. Romanian Biotechnological Letters 24 (2), 301-307. https://romanianbiotechnologicalletters.wordpress.com/2017/12/08/hepatoprotective-effects-of-chlorogenic-acid-under-hyperglycemic-conditions/

Geicu Ovidiu Ionuț

Titlul tezei de doctorat: Compuși de glicare avansată legați la proteine și impactul acestora asupra sănătății umane și în alimentație

Cod dosar platforma REI: F-CA-20505/22.03.2019

• Geicu OI., Stanca L., Dinischiotu A., Serban A.I., 2018. Proteomic and immunochemical approaches to understanding the glycation behaviour of the casein and β-lactoglobulin fractions of flavoured drinks under UHT processing conditions. Scientific Reports 8 (1), 1-15. https://www.nature.com/articles/s41598-018-28943-4

Gheorghe Roxana Olimpia

Titlul tezei de doctorat: Rolul receptorului TRPV1 și al macrofagelor endogene din ganglionii spinali în producerea durerii neuropatice

Cod dosar platforma REI: F-CA-24102/17.09.2019

• Gheorghe R.O., Soca, A., Chirițoiu M., Deftu, A.F., Flonta, M.L., Ristoiu, V. 2018. Long-term exposure to CXCL2 has cytotoxic effects on HEK293T cells stably expressing TRPV1. Romanian Biotechnological Letters, 23 (3), 13647-13653. https://romanianbiotechnologicalletters.wordpress.com/2017/11/16/1-long-term-exposure-to-cxcl2-has-cytotoxic-effects-on-hek293t-cells-stably-expressing-trpv1/
• Deftu AT., Ciorescu R., Gheorghe RO., Mihăilescu D., Ristoiu V. 2019. CXCL1 and CXCL2 Inhibit the Axon Outgrowth in a Time- and Cell-Type-Dependent Manner in Adult Rat Dorsal Root Ganglia Neurons. Neurochemical Research 44 (9), 2215-2229. https://link.springer.com/article/10.1007/s11064-019-02861-x
• Deftu A., Filippi A., Gheorghe RO., Ristoiu V. 2018. CXCL1 activates TRPV1 via Gi/o protein and actin filaments. Life Sciences, 193, 282-291. https://www.sciencedirect.com/science/article/abs/pii/S0024320517305003?via%3Dihub
• Deftu A, Filippi A, Shibasaki K, Gheorghe RO., Chiritoiu M, Ristoiu V. 2017. CXCL1 and CXCL2 chemokines modulate the activity of TRPV1+/IB4+ cultured rat dorsal root ganglia neurons upon short-term and acute application, Journal of Physiology and Pharmacology, 68 (3), 385-395. http://www.jpp.krakow.pl/journal/archive/06_17/pdf/385_06_17_article.pdf

Hudiță Ariana

Titlul tezei de doctorat: Strategii moderne în abordarea cancerului colorectal

Cod dosar platforma REI: F-CA-22812/09.07.2019

• Hudiță A., Ioana-Lavric V., Zamfir A., Buburuzan L., Ginghină O., Negrei C., Burcea G., Costache M., Ardeleanu C., Radu E., Bârcă M. 2018. Optimization of a flow cytometry method for the approach of liquid biopsy as a theraphy modulation tool in patients with colorectal cancer. Farmacia 66 (5), 853 – 860. https://farmaciajournal.com/issue-articles/optimization-of-a-flow-cytometry-method-for-the-approach-of-liquid-biopsy-as-a-therapy-modulation-tool-in-patients-with-colorectal-cancer/
• Hudiță A., Gălățeanu B., Dinescu S., Costache M., Dinischiotu A., Negrei C., Stan M., Tsatsakis A., Nikitovic D., Lupuliasa D. Balanescu A. 2020. In vitro effects of cetylated fatty acids mixture from celadrin on chondrogenesis and inflammation with impact on osteoarthritis. Cartilage 11(1), 88-97. https://journals.sagepub.com/doi/10.1177/1947603518775798?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
• Gălățeanu B., Hudiță A., Gălățeanu B., Negrei C., Ion R.M., Costache M., Stan M., Nikitovic D., Hayes A.W., Spandidos D.A., Tsatsakis A.M., Ginghină O. 2016. Impact of multicellular tumor spheroids as an in vivo-like tumor model on anticancer drug response. International Journal of Oncology 48(6), 2295-2302. https://www.spandidos-publications.com/ijo/48/6/2295
• Costea T., Hudiță A.,  Ciolac O.A., Gălățeanu B., Ginghină O., Costache M., Ganea C., Mocanu, MM. 2018. Chemoprevention of Colorectal Cancer by Dietary Compounds. International Journal of Molecular Sciences 19 (12), 3787. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321468/

Ibraheem Sumayah

Titlul tezei de doctorat: Bioactivity of silver nanoparticles against some of multidrug resistant bacterial isolates

Cod dosar platforma REI: F-CA-23052/16.07.2019

• Sumayah Abdulhussien Ibraheem, Haitham Ali Kadhem, Sarmed Al Hadeethi, Majid Sakhi Jabir, Grigore R., Popa M., Gheorghe I., Mihailescu DF. 2019. Effects of silvernanoparticles on nosocomial Pseudomonas aeruginosa strain an alternative approach for antimicrobial therapy. Romanian Biotechnological Letters 24 (2), 286-293. https://www.cabdirect.org/globalhealth/abstract/20203320846

Jaberi Ahmed Kareem Hammood

Titlul tezei de doctorat: The antimicrobial effect of zein nanoparticles loaded with different metal ions

Cod dosar platforma REI:  F-CA-18456/09.01.2019

• Jaberi AKH., Saedi JAL., Mernea M., Petrescu L., Călborean O., Vasile I., Mihăilescu DF. 2019. Lipopolysaccharides association on the surface of a silicon crystal addressed by thz spectroscopy and molecular modelling. Romanian Journal of Biophysics 29 (1), 1-9. https://www.rjb.ro/lipopolysaccharides-association-on-the-surface-of-a-silicon-crystal-addressed-by-thz-spectroscopy-and-molecular-modelling/

Mărginean (Crețu) Georgiana 

Titlul tezei de doctorat: Studiu asupra comunităților de chiroptere din munții Făgăraș și Piatra Craiului

Cod dosar platforma REI: F-CA-19932/27.02.2019

• Mărginean G., Crețu I., Spătaru GC., Chachula OM.  2015. Myotis myotis and Myotis blythii (Mammalia: Chiroptera) preference for the use of Piatra Craiului caves during their mating and hibernation periods. Muzeul Olteniei Craiova. Oltenia. Studii şi comunicări. Ştiinţele Naturii. 31 (2), 167-172. http://biozoojournals.ro/oscsn/cont/31_2/20_Marginean.pdf

Marinescu George Cătălin

Titlul tezei de doctorat: Obținerea biotehnologică a nicotinamid-mononucleotidului în Escherichia coli și studiul potențialului antidiabetic al acestuia

Cod dosar platforma REI: F-CA-20055/06.03.2019

• Marinescu GC., Popescu R.G., Stoian G., Dinischiotu A. 2018. β-nicotinamide mononucleotide (NMN) production in Escherichia coli. Scientific Reports 8 (1), 1-11. https://www.nature.com/articles/s41598-018-30792-0
• Marinescu GC., Popescu R.G., Dinischiotu A. 2018. Size exclusion chromatography method for purification of nicotinamide mononucleotide (NMN) from bacterial cells. Scientific Reports 8 (1), 1-11. https://www.nature.com/articles/s41598-018-22806-8

Moraru Valentina Elena

Titlul tezei de doctorat: Studii ecologice asupra țestoasei de uscat dobrogene (Testudo graeca ibera) în România

Cod dosar platforma REI: F-CA-18167/21.12.2018

• Moraru VE., Buhaciuc E., Măntoiu D.S., Gavril VD., Popescu-Mirceni R. Strugariu A. 2016. The spur-thighed tortoise (Testudo graeca ibera) in Romania: new locality records suggest a more optimistic situation. North-Western Journal of Zoology 12 (2), 396-400. https://biozoojournals.ro/nwjz/content/v12n2/nwjz_e162502_Moraru.pdf

Najee Haifaa Bawie Najee

Titlul tezei de doctorat: Biological activity and mechanisms of action of some vegetal oils on antibiotic resistant and biofilm forming microorganisms

Cod dosar platforma REI: F-CA-21786/23.05.2019

• Haifaa Najee., Kamerzan C., Marutescu M., Gheorghe I., Popa M., Pircalabioru G., Chifiriuc MC., Lazar V. 2018.  Antifungal activity of some medicinal plant extracts against Candida albicans nosocomial isolates. Romanian Biotechnological Letters 23 (6) 14073-14076.  https://www.e-repository.org/rbl/vol.23/iss.6/1.pdf
• Haifaa Bawie Najee., Alkurjia D., Almahdawy O., Kamerzan C., Marutescu M., Gheorghe I., Popa M., Chifiriuc., Lazăr V. 2018.  Antimicrobial activity of Olea europaea fatty oil against multi-drug resistant and biofilm forming microorganisms. Journal Notulae Scientia Biologicae, Vol.10 (4): 498-502. https://notulaebiologicae.ro/index.php/nsb/article/view/10404

Nica Ionela Cristina

Titlul tezei de doctorat: Studiul mecanismelor biochimice induse de nanoparticule de TiO₂ la nivel dermal şi pulmonar

Cod dosar platforma REI: F-CA-20025/05.03.2019

• Nica I.C., Stan M.S., Popa M., Chifiriuc M.C., Pircalabioru G.G., Lazar V., Dumitrescu I., Diamandescu L., Feder M., Baibarac M., Cernea M., Maraloiu V.A., Popescu T., Dinischiotu A. 2017. Development and biocompatibility evaluation of photocatalytic TiO₂/reduced graphene oxide-based nanoparticles designed for self-cleaning purposes. Nanomaterials 7, 279. https://www.mdpi.com/2079-4991/7/9/279
• Nica IC., Stan MS., Popa M., Chifiriuc MC., Lazar V., Pircalabioru GG., Dumitrescu I., Ignat M., Feder M., Tanase LC., Mercioniu I., Diamandescu L., Dinischiotu A. 2017. Interaction of new developed TiO₂-based photocatalytic nanoparticles with pathogenic microorganisms and human dermal and pulmonary fibroblasts. International Journal of Molecular Sciences 18, 249. https://www.mdpi.com/1422-0067/18/2/249
• Nica I.C., Stan M.S., Dinischiotu A., Popa M., Chifiriuc M.C., Lazar V., Pircalabioru G.G., Bezirtzoglou E., Iordache O.G., Varzaru E., Dumitrescu I., Feder M., Vasiliu F., Mercioniu I., Diamandescu L. 2016. Innovative self-cleaning and biocompatible polyester textiles nano-decorated with Fe–N-doped titanium dioxide. Nanomaterials 6, 214. https://www.mdpi.com/2079-4991/6/11/214

Oprea Georgeta Cristina

Titlul tezei de doctorat: Studiul fenotipic şi molecular al factorilor de virulenţă la Bordetella pertussis în vederea optimizării diagnosticului şi monitorizării tusei convulsive

Cod dosar platforma REI: F-CA-18519/10.01.2019

• Oprea GC.,  Lazăr V. 2018. Expression of adhesins by some Bordetella pertussis strains isolated in Romania in different time periods. Studia Universitatis Babeş – Bolyai, Biologia LXIII, 2, 73-80. http://studia.ubbcluj.ro/download/pdf/Biologia_pdf/2018_2/05.pdf

Porumbel (Capdemai) Iuliana 

Titlul tezei de doctorat: Profiluri de rezistenţă la antibiotice beta-lactamice ale bacililor gram negativi de importanță medicală

Cod dosar platforma REI: F-CA-20940/08.04.2019

• Porumbel I., Chelariu M., Gheorghe .I, Curutiu C., Popa M., Delcaru C., Grosu M., Grigore R., Bertesteanu S., Lazar V., Dimov T. 2018. Genotypic characterization of virulence and resistance markers in ESBL positive Escherichia coli strains isolated from ambulatory urinary tract infections. Romanian Biotechnological Letters. 23 (3), 13572-13580. https://www.e-repository.org/rbl/vol.23/iss.3/3.pdf

Radu (Icriverzi) Madalina 

Titlul tezei de doctorat: Evaluarea in vitro a răspunsului celular la materiale cu suprafeţe modificate cu aplicaţii în regenerarea osoasă

Cod dosar platforma REI: F-CA-25206/16.10.2019

• Icriverzi M., Rusen L., Brajnicov S., Bonciu A., Dinescu M., Cimpean A., Evans W.R., Dinca V., Roseanu A. 2019. Macrophage in vitro response on hybrid Coatings obtained by matrix assisted pulsed laser evaporation. Coatings, 9 (4), 236. https://www.mdpi.com/2079-6412/9/4/236
• Icriverzi M., Rusen L., Sima LE., Moldovan A., Brajnicov S., Bonciu A., Mihailescu N., Dinescu M., Cimpean A., Roseanu A. 2018. In vitro behavior of human mesenchymal stem cells on poly (N-isopropylacrylamide) based biointerfaces obtained by matrix assisted pulsed laser evaporation. Applied Surface Science 440, 712-724. https://www.sciencedirect.com/science/article/abs/pii/S0169433218302186

Shalal Omar Sadik

Titlul tezei de doctorat: Phenotypic and genotypic characterization of pathogenicity features in Candida albicans clinical isolates

Cod dosar platforma REI: F-CA-24534/03.10.2019

• Sadik O., Ditu LM, Gheorghe I, Gradisteanu Pircalabioru G, Bleotu C, Banu O, Merezeanu N, Lupu AC, Lazar V, Chifiriuc MC. Adherence and Biofilm Formation in Candida albicans Strains Isolated from Different Infection Sites in Hospitalized Patients. Revista de Chimie, 12 (68), 2832-2835. https://revistadechimie.ro/Articles.asp?ID=5988

Silea Florea Codruța

Titlul tezei de doctorat: Investigarea interrelațiilor dintre inflamație, infecția spermatică și variațiile parametrilor seminali în infertilitatea masculină

Cod dosar platforma REI: F-CA-20973/09.04.2019

• Silea C., Cucu IA.,  Zarnescu O., Stoian AP., Motofei IG., Bratu OG., Pircalabioru GG., Chifiriuc MC. 2019. Influence of age on sperm parameters in men with suspected infertility. Romanian Biotechnological Letters. 24 (1), 82-90. https://www.e-repository.org/rbl/vol.24/iss.1/10.pdf

Stanislav Alexandra Alina

Titlul tezei de doctorat: Factori genetici în sindromul metabolic, obezitate, diabet zaharat și hipertensiune arterială

Cod dosar platforma REI: F-CA-20967/08.04.2019

• Stanislav AA., Vassu-Dimov T., Iacob MM., Botezatu A., Arsene C., Burlibasa L., Bodron P., Sarghie L., Cucu N., Alexandrescu L. 2018. Investigation of fat mass and obesity associated (FTO) gene polymorphism in Romanian populayion. Biointerface Research in Applied Chemistry 8 (6), 3710-3718. https://www.researchgate.net/publication/329933356_Investigation_of_fat_mass_and_obesity_associated_FTO_gene_polymorphism_in_Romanian_population

Staraș Adela Ioana

Titlul tezei de doctorat: Studii in vitro de evaluare a biocompatibilității unor materiale cu suprafață modificată pentru regenerare osoasă

Cod dosar platforma REI: F-CA-16231/30.10.2018

• Neacsu P., Staras AI., Voicu SI., Ionascu I., Soare T., Uzun S., Cojocaru VD., Pandele AM., Croitoru SM., Miculescu F., Cotrut, CM., Dan I., Cimpean A. 2017. Characterization and in vitro and in vivo assessment of a novel cellulose acetate-coated Mg-based alloy for orthopedic applications. Materials, 10, 686. https://www.mdpi.com/1996-1944/10/7/686

Telcian Ancuța

Titlul tezei de doctorat: Evaluarea proprietăților anti-biofilm ale unor suprafețe protetice nanostructurate

Cod dosar platforma REI: F-CA-15220/01.10.2018

• Telcian A., Hussien MD., Chifiriuc MC.,  Bleotu C., Holban AM., Curutiu C.,, Grosu E, Ficai A., Mihaescu G., Grigore R., Ditu LM. 2017. Assessment of the anti-biofilm activity and biocompatibilitx of novel PE and PVC polymers. Romanian Biotechnological Letters, 22 (5), 12997-13004. https://e-repository.org/rbl/vol.22/iss.5/17.pdf

Udrea Ana-Maria

Titlul tezei de doctorat: Noi abordări terapeutice ale compușilor naturali prin tehnici de farmacologie computațională

Cod dosar platforma REI: F-CA-15521/11.10.2018

• Udrea AM., Puia A., Shaposhnikov S.. Avram S. 2018. Computational approaches of new perspectives in the treatment of depression during pregnancy. Farmacia,  66 (4) 680-687. https://farmaciajournal.com/issue-articles/computational-approaches-of-new-perspectives-in-the-treatment-of-depression-during-pregnancy/

Velican Alexandra Mihaela

Titlul tezei de doctorat: Optimizarea unor metode rapide de diagnostic microbiologic şi de determinare a sensibilităţii la antibiotice cu ajutorul citometriei în flux

Cod dosar platforma REI: F-CA-24006/11.09.2019

• Velican AM., Kamerzan C., Maruțescu L., Lambert C., Chifiriuc MC. 2019. The development of an analysis protocol based on flow cytometry for rapid detection of uropathogenic E. coli in artificially contaminated urine samples. Romanian Biotechnological Letters 24 (4), 563-570. https://www.e-repository.org/rbl/vol.24/iss.4/1.pdf